It has also been effectively used as herbal and alternative medicine in common cold, flu, and as a digestive aid. It has a cooling, analgesic, and muscle-relaxing effect through transient receptor potential cation channel subfamily M member 8, kappa, and voltage-gated sodium channel receptors, respectively. We here report for the 1 st time a case of fatal menthol toxicity after acute exposure.
A twenty-one-year-old farmer living in a village of Uttar Pradesh, India, was brought to our emergency department in unconscious state. The history suggested that 4 days ago, he was asked to clean a tank in a peppermint factory. He got down inside the tank and soon after the inhalation of toxic fumes, he was found in unconscious state.
It took an hour to bring him out from the tank. He remained unconscious and then developed recurrent convulsions and intermittent hematuria. The recurrent seizure activity was controlled with intravenous midazolam followed by intravenous levetiracetam. Supportive treatment such as nasogastric lavage and intravenous fluids were also given.
On the further history and clinical examination, there was no upper or lower limb weakness, or myoclonic jerks. Pupils were normal in size and were reactive to light, and there was no neck rigidity. The patient had an increased muscle tone in all 4 limbs, and the deep tendon reflexes were exaggerated. There was no history of substance abuse, smoking, alcohol intake, and medications. The patient's past medical history was also noncontributory.
His blood results showed hemoglobin Chest radiograph [ Figure 1 ] and electrocardiogram [ Figure 2 ], cerebrospinal fluid examination were within normal limits. Urine culture was sterile.
Urine toxicology screen was positive for benzodiazepine, probably secondary to intravenous midazolam, which was given to control the seizures. His arterial blood gas showed pH 7. Noncontrast computed tomography brain showed loss of gray-white matter differentiation and evidence of cerebral edema [ Figure 3 ]. The patient remained in a coma due to low GCS patient was intubated to protect his airways. He was continued on levetiracetam, but sodium valproate and midazolam infusion was added to control the seizures.
The patient remained unconscious with poorly controlled recurrent seizures. During his hospital stay, he developed ventilator associated pneumonia, sepsis with shock, and acute renal dysfunction. Broad spectrum antibiotics, intravenous fluids, nor-adrenaline, and dopamine were added along with other supportive measures.
Unfortunately, the patient expired after 10 days of hospitalization. The goal is to drain the fluid and make it easier for you to…. Popcorn lung is caused by exposure to toxic chemicals found in microwaveable popcorn factories and e-cigarettes.
Symptoms include flu-like illness…. A pulmonologist is a doctor who focuses on the respiratory system. Discover the conditions they treat such as COPD , exams they conduct, and much…. Health Conditions Discover Plan Connect. Can You Overdose on Cough Drops? Medically reviewed by Alan Carter, Pharm. Symptoms See a doctor Treatment Outlook Prevention Menthol poisoning Cough drops, sometimes called throat lozenges, help to soothe the throat and curb the reflex that makes you cough.
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What Is Diaphragmatic Breathing? Thoracentesis: What You Need to Know. Medically reviewed by Raj Dasgupta, MD. Wisconsin Research and Education Network Senior Scientist David Hahn, MD, led a study showing that too many cough drops — especially those containing menthol — may actually make coughs more severe.
Inspired by that observation, a new study of more than patients has shown that too many cough drops — especially those containing menthol — may actually make coughs more severe. Robert Mead, a family-medicine physician with Bellin Health, followed up his original observation by asking patients with persistent and unexplained coughs to stop using cough drops.
He observed that coughs then resolved over a matter of days. Some went through an entire bag 20 in one day! Mead went to Dr.
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